Investing

Stocks making big moves midday: ORCL ASTS, RVMD

AppFolio

The cloud-based business software provider saw a 7% increase after KeyBanc upgraded its rating from equal weight to overweight. The firm set a 12-month price target of $285, according to FactSet’s StreetAccount service.

AST SpaceMobile

Shares of this space-based broadband cellular network dropped by 6% after experiencing a more than 100% increase over the past month. Barclays downgraded its investment rating from overweight to underweight, maintaining a price target of $60, as reported by StreetAccount.

Revolution Medicines

This late-stage clinical oncology company surged by 10% after announcing that the FDA granted a voucher for daraxonrasib (RMC-6236) under the National Priority Voucher pilot program. This multi-selective inhibitor targets patients with metastatic pancreatic ductal adenocarcinoma and metastatic non-small cell lung cancer.

Core Scientific

The quantum computing company experienced a decline of over 5% following CoreWeave’s response to investor Two Seas Capital, which opposed the acquisition of Core Scientific. CoreWeave described its offer as “best and final.”

State Street

The asset manager’s shares fell by more than 3% after reporting mixed third-quarter results. Although earnings and revenue exceeded expectations, net interest income of $715 million fell short of the FactSet estimate of $740.2 million.

Regional Banks

This sector saw a slight uptick after a broader market decline on Thursday. Zions rallied over 4% following a Baird upgrade, while Western Alliance rose by 2%. The SPDR S&P Regional Banking ETF (KRE) advanced by 1%.

Jefferies

Shares of the investment bank jumped 4.2% after a significant drop of more than 10% the previous day. Oppenheimer upgraded the stock to outperform, citing Jefferies’ limited exposure to First Brands.

CSX

The Jacksonville-based railroad company added 3% after reporting better-than-expected third-quarter earnings. CSX posted adjusted earnings of 44 cents per share on $3.59 billion in revenue, surpassing analyst expectations of 42 cents per share and $3.58 billion in revenue.

Interactive Brokers Group

Shares fell by 3% despite an earnings report that beat expectations for the third quarter. The company recorded earnings of 57 cents per share, excluding items, and $1.61 billion in revenue, exceeding the LSEG estimates of 54 cents and $1.52 billion.

Oracle

The software stock declined by 7%, reversing some of the gains made in Thursday’s session. Oracle confirmed a cloud computing deal with Meta on Thursday.

Bank OZK

This regional bank slipped 3% after third-quarter earnings missed expectations, compounding losses from Thursday’s regional bank sell-off. Bank OZK earned $1.59 per share, falling short of the consensus forecast of $1.66 per share from analysts surveyed by FactSet.

Pharmaceutical Stocks

Shares of Novo Nordisk and Eli Lilly fell between 3% and 4% after former President Donald Trump suggested that obesity drug costs could be “much lower.” However, Dr. Mehmet Oz, administrator of the Centers for Medicare & Medicaid Services, noted that the prices of popular GLP-1 medications had not yet been negotiated by the White House.

Fifth Third Bancorp

Shares of the bank, which recently announced its acquisition of Comerica, gained 1% following a better-than-expected third-quarter earnings report. Fifth Third earned 91 cents per share and $2.31 billion in revenue, surpassing analyst forecasts of 87 cents and $2.28 billion.

Micron Technology

Shares traded 2% lower after reports indicated that Micron would exit the server chips business in China. The company’s operations in the Asian market have struggled to recover following a 2023 ban on its products in critical infrastructure.

American Express

The financial stock rose by 6% after exceeding expectations for the third quarter and raising its full-year guidance. American Express reported earnings of $4.14 per share on $18.43 billion in revenue, while analysts had anticipated $4 per share and $18.05 billion.

Truist Financial

The bank’s stock increased by 3.5% following a stronger-than-expected third-quarter earnings report. Truist earned $1.07 per share, excluding items, and $5.24 billion in revenue, beating analyst expectations of $1 and $5.20 billion.

Intuitive Machines

This space technology stock rallied 3% after Deutsche Bank upgraded its rating from hold to buy, citing an attractive risk-to-reward ratio and upcoming commercial catalysts.

— CNBC’s Alex Harring, Fred Imbert, and Pia Singh contributed reporting. (Learn the best 2026 strategies from inside the NYSE with Josh Brown and others at CNBC PRO Live. Tickets and info here.)